教員データベース
森 誠司
| 役職 | 臨床検査学科 副学科長／教授 |
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| 担当科目 | 基礎ゼミナール、IPW論、生化学、生化学各論、生化学実習、バイオテクノロジー演習、遺伝子検査学、遺伝子検査学実習、放射性同位元素検査学、検査技術科学序論、総合演習Ⅰ・Ⅱ・Ⅲ、臨地実習、卒業研究Ⅰ・Ⅱ |
| 研究テーマ | ・分子生物学 ・細胞生物学 ・腫瘍学 |
| 業績詳細リンク | https://ken.morinomiya-u.ac.jp/mumhp/KgApp?kyoinId=ymibgboeggy |
| 経歴 | 2003年 大阪大学大学院医学系研究科博士課程修了 博士（保健学） 2003年 米国カリフォルニア大学 デービス メディカルセンター 研究員 2006年 米国テキサス大学MDアンダーソン癌センター 研究員 2007年 大阪大学大学院医学系研究科保健学専攻 助教 2014年 大阪大学大学院医学系研究科 特任准教授 2016年 森ノ宮医療大学保健医療学部臨床検査学科 教授 |
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| 所属学会 | 日本医学検査学会、日本分子生物学会、ナノ・バイオメディカル学会、日本がん転移学会、日本癌学会 |
| 著書 | 1．Mori S and Takada Y., FGF1 (fibroblast growth factor 1 (acidic)). Atlas Genet Cytogenet Oncol Haematol.18(3):164-168. 2014 2．2002年 スタンダード病理学 病理検査のすべて 文光堂 |
| 論文 | 1. Mori S, Hatori N, Kawaguchi N, Hamada Y, Shih TC, Wu CY, Lam KS, Matsuura N, Yamamoto H, Takada YK, Takada Y. The integrin-binding defective FGF2 mutants potently suppress FGF2 signaling and angiogenesis. Bioscience Reports. 37(2), pii: BSR20170173, 2017 2. Uchinaka A, Kawaguchi N, Ban T, Hamada Y, Mori S, Maeno Y, Sawa Y, Nagata K, Yamamoto H., Evaluation of dermal wound healing activity of synthetic peptide SVVYGLR. Biochem Biophys Res Commun. 491(3):714-720, 2017 3. Tsubouchi K, Minami K, Hayashi N, Yokoyama Y, Mori S, Yamamoto H, Koizumi M., The CD44 standard isoform contributes to radioresistance of pancreatic cancer cells. Journal of Radiation Research. 2017 4. Uchinaka A, Tasaka K, Mizuno Y, Maeno Y, Ban T, Mori S, Hamada Y, Miyagawa S, Saito A, Sawa Y, Matsuura N, Nagata K, Yamamoto H, Kawaguchi N, Laminin α2-secreting fibroblasts enhance the therapeutic effect of skeletal myoblast sheets. European Journal of Cardio-Thoracic Surgery. 1;51(3):457-464, 2017 5. Minami K, Hamada Y, Kawaguchi N, Mori S, Nakatani K, Tsubouchi K, Hayashi N, Yamamoto H, Koizumi M, The Combined Effect of an Anti-microtubule Agent TZT-1027 and Radiation on Tumor Angiogenesis, Nano Biomedicine. 8(2), 83-90, 2016 6. Mori S, Kodaira M, Ito A, Okazaki M, Kawaguchi N, Hamada Y, Takada Y, Matsuura N, Enhanced expression of integrin αvβ3 induced by TGF-β is required for the enhancing effect of fibroblast growth factor 1 (FGF1) in TGF-β-induced epithelial-mesenchymal transition (EMT) in mammary epithelial cells. PLoS One. 10, e0137486. 2015 7. Mizuno Y, Uchinaka A, Horii Y, Mori S, Hamada Y, Miyagawa S, Saito A, Sawa Y, Matsuura N, Kawaguchi N., Improvement of cardiac function after implanting the osteopontin-derived peptide SVVYGLR in a hamster model of dilated cardiomyopathy. Interact Cardiovasc Thorac Surg. 4, 506-514, 2015 8. Uchinaka A, Hamada Y, Mori S, Miyagawa S, Saito A, Sawa Y, Matsuura N, Yamamoto H, Kawaguchi N., SVVYGLR motif of the thrombin-cleaved N-terminal osteopontin fragment enhances the synthesis of collagen type III in myocardial fibrosis. Mol Cell Biochem. 408, 191-203, 2015 9. Nakane K, Takiyama A, Mori S, Matsuura N.: Homology-based method for detecting regions of interest in colonic digital images. Diagn Pathol. 10:36, 2015 10. Kojima Y, Hamada Y, Kawaguchi N, Mori S, Daito K, Uchinaka A, Hayakawa N, Arita K, Nagase Y, Matsuura N., Effects of Moxibustion on Body Core Temperature Responses in Rats. Nano Biomedicine. 6, 12-20, 2014 11. Minami K, Koizumi M, Hamada Y, Mori S, Kawaguchi N, Manabe M, Imaizumi H, Nakatani K, Matsuura N., The Effect of Carbon Ion Beam Irradiation for Hypoxia-Mediated Invasion of Glioblastoma. Nano Biomedicine. 6, 1-11, 2014 12. Uchinaka A, Kawaguchi N, Mori S, Hamada Y, Miyagawa S, Saito A, Sawa Y, Matsuura N., Tissue inhibitor of metalloproteinase-1 and -3 improves cardiac function in an ischemic cardiomyopathy model rat. Tissue Eng Part A. 2014 Nov;20 (21-22):3073-84. 13. Mori S, Tran V, Nishikawa K, Kaneda T, Hamada Y, Kawaguchi N, Fujita M, Takada YK, Matsuura N, Zhao M, Takada Y., A dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesis. PLoS One. 8, e57927. 2013 14. Uchinaka A, Kawaguchi N, Hamada Y, Mori S, Miyagawa S, Saito A, Sawa Y, Matsuura N., Transplantation of myoblast sheets that secrete the novel peptide SVVYGLR improves cardiac function in failing hearts. Cardiovasc Res. 99, 102-110. 2013. 15. Mori S and Takada Y., Crosstalk between Fibroblast Growth Factor (FGF) Receptor and Integrin through Direct Integrin Binding to FGF and Resulting Integrin-FGF-FGFR Ternary Complex Formation. Med. Sci. 1, 20-36. 2013 16. Hamada Y, Fujitani W, Kawaguchi N, Daito K, Niido T, Uchinaka A, Mori S, Kojima Y, Manabe M, Nishida K, Arita K, Nakano T, Matsuura N., The preparation of PLLA/calcium phosphate hybrid composite and its evaluation of biocompatibility. Dent Mater J. 31, 1087-1096. 2012 17. Uchinaka A, Kawaguchi N, Hamada Y, Miyagawa S, Saito A, Mori S, Sawa Y, Matsuura N., Transplantation of elastin-secreting myoblast sheets improves cardiac function in infarcted rat heart. Mol Cell Biochem. 368, 203-214. 2012 18. Neal CL, Xu J, Li P, Mori S, Yang J, Neal NN, Zhou X, Wyszomierski SL, Yu D., Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit. Oncogene. 31, 897-906. 2012 19. Yokoyama Y, Mori S, Hamada Y, Hieda M, Kawaguchi N, Shaker M, Tao Y, Yoshidome K, Tsujimoto M, Matsuura N., Platelet-Derived Growth Factor Regulates Breast Cancer Progression via β-Catenin Expression. Pathobiology. 78, 253-260. 2011 20. Shaker M, Yokoyama Y, Mori S, Tsujimoto M, Kawaguchi N, Kiyono T, Nakano T, Matsuura N., Aberrant expression of disintegrin-metalloprotease proteins in the formation and progression of uterine cervical cancer. Pathobiology. 78, 149-161. 2011 21. Yamaji S, Saegusa J, Ieguchi K, Fujita M, Mori S, Takada YK, Takada Y., A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist. PLoS One. 5:e10273, 2010 22. Ito E, Yana I, Fujita C, Irifune A, Takeda M, Madachi A, Mori S, Hamada Y, Kawaguchi N, Matsuura N., The role of MT2-MMP in cancer progression.: Biochem Biophys Res Commun. 393, 222-227, 2010 23. Fujitani W, Hamada Y, Kawaguchi N, Mori S, Daito K, Uchinaka A, Matsumoto T, Kojima Y, Daito M, Nakano T, Matsuura N., Synthesis of hydroxyapatite contining manganese and its evaluation of biocompatibility. Nano Biomedicine. 2, 37-46, 2010 24. Mori S, Wu CY, Yamaji S, Saegusa J, Shi B, Ma Z, Kuwabara Y, Lam KS, Isseroff RR, Takada YK, Takada Y., Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling. J Biol Chem. 283, 18066-18075, 2008 25. Wu P. L., Lee S. C., Chuang C. C., Mori S., Akakura N., Wu W. G., Takada Y., Non-cytotoxic cobra cardiotoxin A5 binds to alpha(v)beta3 integrin and inhibits bone resorption. Identification of cardiotoxins as non-RGD integrin-binding proteins of the Ly-6 family. J Biol Chem. 281, 7937-7945, 2006 26. Yamamoto Y., Hirakawa E., Mori S., Hamada Y., Kawaguchi N., Matsuura N., Cleavage of carcinoembryonic antigen induces metastatic potential in colorectal carcinoma. Biochem Biophys Res Commun. 333, 223-229, 2005 27. Tanaka M, Nanba D, Mori S, Shiba F, Ishiguro H, Yoshino K, Matsuura N, Higashiyama S., ADAM binding protein Eve-1 is required for ectodomain shedding of epidermal growth factor receptor ligands. J Biol Chem. 279, 41950-41959, 2004 28. Mori, S., Tanaka, M., Nanba, D., Nishiwaki, E., Ishiguro, H., Higashiyama, S., Matsuura, N., PACSIN3 binds ADAM12/Meltrin  and upregulates ectodomain shedding of heparin-binding EGF-like growth factor. J Biol Chem. 278, 46029-46034, 2003 29. Takahashi, Y., Teshima, T., Kawaguchi, N., Hamada, Y., Mori, S., Madachi, A., Ikeda, S., Mizuno, H., Ogata, T., Nojima, K., Furusawa, Y., and Matsuura, N., Heavy ion irradiation inhibits in vitro angiogenesis even at sublethal dose. Cancer Res. 63, 4253-4257, 2003 30. Tomoda K., Kubota Y., Arata Y., Mori S., Maeda M., Tanaka T., Yoshida M., Yoneda-Kato N., and Kato JY., The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex. J Biol Chem. 277, 2302-2310, 2002 31. 松浦成昭、森誠司、内仲彩子、山本浩文 大腸癌のリンパ節中微量癌細胞検出の意義 大腸癌Frontier 2012年 32. 松浦成昭、伊東絵望子、横山雄起、森誠司 転移におけるケモカインの役割 Surgery Frontier 2009年 33. 松浦成昭、足立恵理、田邊正喜、森誠司 インテグリンとシグナル伝達 現代医療 2003年 34. Matsuura, N., Onishi, N., Madachi, A., Mori, S. Prospect for cancer therapy by angiogenesis inhibitors Biotherapy 2002年 35. Matsuura, N., Fujiwara, A., Mori, S., Yamaguchi, M., The role of integrin in the invasion and metastasis of gastric cancer. Nippon Rinsho 2001年 |